The association of SNPs in Hsp90β gene 5′ flanking region with thermo tolerance traits and tissue mRNA expression in two chicken breeds

@article{Chen2013TheAO,
  title={The association of SNPs in Hsp90β gene 5′ flanking region with thermo tolerance traits and tissue mRNA expression in two chicken breeds},
  author={Zhuo-Yu Chen and J Gan and Xiong Xiao and Li-yan Jiang and Xi-Quan Zhang and Qing-Bin Luo},
  journal={Molecular Biology Reports},
  year={2013},
  volume={40},
  pages={5295-5306}
}
Thermo stress induces heat shock proteins (HSPs) expression and HSP90 family is one of them that has been reported to involve in cellular protection against heat stress. But whether there is any association of genetic variation in the Hsp90β gene in chicken with thermo tolerance is still unknown. Direct sequencing was used to detect possible SNPs in Hsp90β gene 5′ flanking region in 3 chicken breeds (n = 663). Six mutations, among which 2 SNPs were chosen and genotypes were analyzed with PCR… CONTINUE READING
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