The association of HLA-DRB1 alleles with antineutrophil cytoplasmic antibody-associated systemic vasculitis in Chinese patients.

@article{Luo2011TheAO,
  title={The association of HLA-DRB1 alleles with antineutrophil cytoplasmic antibody-associated systemic vasculitis in Chinese patients.},
  author={Huan Luo and Min Chen and Rui Yang and Peng-cheng Xu and Ming-Hui Zhao},
  journal={Human immunology},
  year={2011},
  volume={72 5},
  pages={422-5}
}
Antineutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitis (AASV) is a group of autoimmune diseases. The human leukocyte antigen (HLA) system is devoted to the pathogenesis of these autoimmune diseases. The present study aimed to investigate the distribution of HLA-DRB1 alleles in Chinese AASV patients and its potential association with clinical and pathologic characteristics. This study included 152 Chinese patients with AASV and 200 healthy controls. Typing of HLA-DRB1 alleles… CONTINUE READING