The association of CLOCK gene T3111C polymorphism and hPER3 gene 54-nucleotide repeat polymorphism with Chinese Han people schizophrenics

@article{Zhang2010TheAO,
  title={The association of CLOCK gene T3111C polymorphism and hPER3 gene 54-nucleotide repeat polymorphism with Chinese Han people schizophrenics},
  author={Jing Zhang and Ga Liao and Chang Liu and Lei Sun and Yanyou Liu and Yuhui Wang and Zhou Jiang and Zhengrong Wang},
  journal={Molecular Biology Reports},
  year={2010},
  volume={38},
  pages={349-354}
}
Many reports have shown that the biologic rhythm could be altered due to mutations of circadian gene hClock or hPeriod, and the mutations of circadian genes have some relationship with psychosis according to recent studies. A preliminary study has been conducted to examine wether the T3111C single nucleotide polymorphism of the hClock gene or the length polymorphism of the hPer3 gene is associated with the development of schizophrenia. The samples from schizophrenics (n = 148, male: 57.4… CONTINUE READING

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