The association between weight change and symptom reduction in the CATIE schizophrenia trial.

Abstract

BACKGROUND Weight gain and changes in metabolic indicators associated with some antipsychotics may be related to symptom improvement and thus an unavoidable correlate of clinical benefit. METHODS Data from the CATIE schizophrenia trial comparing the effectiveness of perphenazine, olanzapine, risperidone, quetiapine and ziprasidone in a randomized, double… (More)
DOI: 10.1016/j.schres.2011.01.022

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