The association between the methionine/valine (M/V) polymorphism (rs1799990) in the PRNP gene and the risk of Alzheimer disease: An update by meta-analysis

@article{He2013TheAB,
  title={The association between the methionine/valine (M/V) polymorphism (rs1799990) in the PRNP gene and the risk of Alzheimer disease: An update by meta-analysis},
  author={Jie He and X. Li and Jiqiao Yang and Jichong Huang and H. Fan},
  journal={Journal of the Neurological Sciences},
  year={2013},
  volume={326},
  pages={89-95}
}
  • Jie He, X. Li, +2 authors H. Fan
  • Published 2013
  • Biology, Medicine
  • Journal of the Neurological Sciences
  • BACKGROUND The M/V polymorphism in the PRNP gene has been extensively examined for the association to the risk of Alzheimer disease (AD); however, results from different studies have been inconsistent. The aim of this study is to evaluate the association between the M/V polymorphism in the PRNP gene and the risk of AD. METHODS A meta-analysis was carried out to analyze the association between the M/V polymorphism in the PRNP gene and the risk of AD. RESULTS A total of 4228 cases and 4324… CONTINUE READING
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