• Corpus ID: 53359369

The association between steroid hormones and cognitive performance in adulthood

@inproceedings{Thilers2009TheAB,
  title={The association between steroid hormones and cognitive performance in adulthood},
  author={Petra Thilers},
  year={2009}
}
ENGLISH The aim of this thesis was to investigate whether endogenous estrogen and testosterone were associated with cognitive performance in adulthood and whether hand preference affected the pattern of sex differences in cognitive performance. The analyses in Studies I-IV were based on data from the Betula project in Umea, Sweden; a population-based longitudinal study on aging and memory. At the second follow-up, there were 3011 participants between 35 and 90 years of age, some entering the… 
9 Citations
Sex steroids to maintain cognitive function in women after the menopause: a meta-analyses of treatment trials.
TLDR
A meta-analyses included 36 randomised treatment trials and indicated that, contrary to expectations, age of women and duration of time elapsed when treatment was initiated since menopause ('window of opportunity' hypothesis) did not significantly affect treatment outcome, nor did it matter whether women were symptomatic or not.
Salivary testosterone levels are unrelated to handedness or cerebral lateralization for language
TLDR
The present study investigated hormonal effects on laterality using adult salivary T levels, to explore the adequacy of competing theories: the Geschwind, Behan and Galaburda, the callosal, and the sexual differentiation hypotheses.
Mechanisms of women's own-gender bias and sex differences in memory for faces
There are sex differences in some cognitive functions. For example, earlier studies have shown that women outperform men on face recognition tasks, and women, in contrast to men, show an own-gender
Oral health & olfactory function : what can they tell us about cognitive ageing?
TLDR
Poor oral health is associated with accelerated cognitive decline and brain ageing, whereas, olfactory deficits may reflect loss of brain integrity in old age.
Physical functioning in old age: Temporal trends and geographical variation in Sweden
TLDR
The aims of the thesis was to examine temporal changes in physical functioning in older adults, to identify underlying development of new disability and functional decline, as well as to explore geographical variation inPhysical functioning between urban and rural elderly habitats.
Dementia and use of drugs : economic modelling and population-based studies
TLDR
The overall aim of this thesis was to investigate epidemiological and health economic aspects of dementia and drug use in older people, through economic modelling and analyses of population-based studies, and introduce a hypothetical economic model of a disease modifying treatment (DMT) for Alzheimer’s disease.
UNEQUAL DRUG TREATMENT: AGE AND EDUCATIONAL DIFFERENCES AMONG OLDER ADULTS
TLDR
The results suggest that older persons with lower levels of education are less likely to receive drug treatment both before and after an osteoporosis-related fracture than their more highly educated counterparts.
DRUG USE IN INSTITUTIONALIZED AND HOME-DWELLING ELDERLY PERSONS
TLDR
Investigating drug use in institutionalized and homedwelling elderly with a special focus on dementia indicates that institutionalization is a potential risk factor for PIDU, and although persons with dementia do not receive less analgesics than persons without dementia, they may be inappropriately treated with psychotropics for their pain.

References

SHOWING 1-10 OF 196 REFERENCES
Endogenous sex hormones and cognitive function in older men.
TLDR
In these older men, low estradiol and high testosterone levels predicted better performance on several tests of cognitive function, suggesting that an optimal level of sex hormones may exist for some cognitive functions.
Endogenous sex hormone levels and cognitive function in aging men
TLDR
Apparent curvilinear associations between T and certain cognitive functions in men suggest an optimal hormone level for particular cognitive tasks and are explained by linear associations in the oldest age category.
Endogenous Estradiol and Testosterone Levels Are Associated with Cognitive Performance in Older Women and Men
TLDR
The associations observed in this small study support the notion that estradiol is protecting verbal memory and possibly also frontal lobe mediated functions in older women and in contrast to the positive findings in women endogenous sex steroids do not appear to be closely linked to better cognition in older men.
Associations between circulating sex steroid hormones and cognition in normal elderly women
TLDR
Both estrogen and testosterone showed associations with cognitive performance, suggesting conditions with higher levels of estrogen are associated with better verbal memory and possibly worse visuospatial ability and that estrogen replacement therapy may enhance, and depress, specific cognitive skills.
Free testosterone and risk for Alzheimer disease in older men
TLDR
Calculated free testosterone concentrations were lower in men who developed Alzheimer disease, and this difference occurred before diagnosis, and future research may determine whether higher endogenous free testosterone levels offer protection against a diagnosis of Alzheimer disease in older men.
Testosterone and cognitive function in ageing men: data from the Florey Adelaide Male Ageing Study (FAMAS).
TLDR
The results from this study suggest that higher levels of endogenous testosterone, particularly in the elderly, may have deleterious effects on cognitive functioning in men.
Endogenous estrogen is not associated with cognitive performance before, during, or after menopause
TLDR
Results showed that there were no differences in cognitive performance among premenopausal, perimenopausal, and postmenopausal groups of women, and there was no associations between blood estrogen levels and cognitive performance.
Interaction between Testosterone and Apolipoprotein E ε4 Status on Cognition in Healthy Older Men
TLDR
This cross-sectional study examined the association between serum testosterone concentrations and cognitive performance in healthy older men, taking into account APOE e4 status in Perth, Western Australia from 2003 to 2004.
Activating effects of cross-sex hormones on cognitive functioning: a study of short-term and long-term hormone effects in transsexuals
TLDR
This study shows that testosterone had an enhancing, and not quickly reversible effect, on spatial ability performance, but no deteriorating effect on verbal fluency in adult women (FMs).
Serum levels of estradiol and testosterone and performance in different cognitive domains in healthy elderly men and women
TLDR
Not all cognitive functions were better with higher levels of sex steroids and effects seemed to be modified by sex; the sex-sensitive tests showing the clearest effects.
...
1
2
3
4
5
...