The association between single-nucleotide polymorphisms of NCF2 and systemic lupus erythematosus in Chinese mainland population

@article{Yu2010TheAB,
  title={The association between single-nucleotide polymorphisms of NCF2 and systemic lupus erythematosus in Chinese mainland population},
  author={Bo Yu and Yuewen Chen and Qi Hui Wu and Ping Li and Yong Shao and Jie Zhang and Qili Zhong and Xi Peng and Hong Yang and Xiaoping Hu and Bancheng Chen and Ming Guan and Jun Wan and Wei Zhang},
  journal={Clinical Rheumatology},
  year={2010},
  volume={30},
  pages={521-527}
}
Systemic lupus erythematosus (SLE) is a complex immune disease. The genetic variation in the NCF2 gene was found to associate with SLE in US and European populations. However, the association of rs10911363 with SLE was not extensively studied in Chinese mainland population. A total of 488 SLE patients and 380 controls were recruited. Unlabeled probe-based high-resolution melting analysis (HRMA) was used in genotyping. HRMA with unlabeled probe successfully distinguished all genotypes. Neither… CONTINUE READING

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Polymorphisms of rs13277113 in NCF2 gene were associated with arthritis and autoantibody production , but not disease risk , of SLE in Chinese population .
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