The association between paracetamol and asthma is still under debate

@article{LouridoCebreiro2017TheAB,
  title={The association between paracetamol and asthma is still under debate},
  author={Tamara Lourido-Cebreiro and F. Salgado and L. Vald{\'e}s and F. Gonz{\'a}lez-Barcala},
  journal={Journal of Asthma},
  year={2017},
  volume={54},
  pages={32 - 38}
}
ABSTRACT Objective: To analyse the relationship between paracetamol and asthma. Data sources: An English literature search using electronic search engines (PubMed and EMBASE) was conducted. Study selections: Articles published in peer-review journals, from 1990 to December 2015 were included. To perform the search for the most suitable and representative articles, keywords were selected (“asthma,” “paracetamol” and “acetaminophen”). The evidence level was rated according to the criteria of the… Expand
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TLDR
There is insufficient evidence to warrant changing guidelines on early life paracetamol exposure at this time, and the association during early pregnancy exposure was highly variable between studies and exposure during infancy appears to be moderately confounded by respiratory tract infections. Expand
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TLDR
Paracetamol consumption is associated with a significant increase in asthma symptoms, and the effect is greater the more often the drug is taken. Expand
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TLDR
In a random effects meta-analysis, weekly use of paracetamol was strongly positively associated with asthma after controlling for confounders, and no association was seen between use of other analgesics and asthma. Expand
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The results of this review are consistent with an increase in the risk of asthma and wheezing in both children and adults exposed to acetaminophen. Expand
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  • Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
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TLDR
Further research is urgently required, in particular randomized‐controlled trials (RCTs) into the long‐term effects of frequent paracetamol use in childhood, to determine the magnitude and characteristics of any such risk. Expand
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TLDR
There was a higher prevalence of new-onset asthma in subjects who reported frequent intake of paracetamol at baseline compared with subjects without this determinant, and the result remained significant after adjusting for sex, age, smoking, BMI, hay fever, eczema, and intake of medications other than par acetamol. Expand
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TLDR
Frequent use of paracetamol may contribute to asthma morbidity and rhinitis in adults and was positively associated with asthma, but aspirin use was not. Expand
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TLDR
The association between maternal paracetamol use during pregnancy and infant wheezing is mainly, if not completely explained by confounding, explainable by confounding. Expand
Is the Effect of Prenatal Paracetamol Exposure on Wheezing in Preschool Children Modified by Asthma in the Mother?
TLDR
The frequent usage of paracetamol during pregnancy is associated with the prevalence of wheezing in offspring during preschool years, and asthma in the mother might modify this association. Expand
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TLDR
In children with a family history of allergic diseases, no association was found between early paracetamol use and risk of subsequent allergic disease after adjustment for respiratory infections or when paracetAMol use was restricted to non-respiratory tract infections. Expand
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