The association between high-activity COMT allele and alcoholism.

@article{er2006TheAB,
  title={The association between high-activity COMT allele and alcoholism.},
  author={Omar {\vS}er{\'y} and William Didden and Vladim{\'i}r Mikes and Ren{\'a}ta Pitelov{\'a} and Vladim{\'i}r Znojil and Petr Zvolsk{\'y}},
  journal={Neuro endocrinology letters},
  year={2006},
  volume={27 1-2},
  pages={231-5}
}
OBJECTIVES The catechol-O-methyltransferase (COMT) is an enzyme involved in the metabolism of dopamine, adrenaline and noradrenaline. The Val158Met polymorphism of the COMT gene has been previously associated with a variability of the COMT activity, and alcoholism. The aim of the present association study was to examine the relationship between the Val158Met polymorphism of the COMT gene and dispositions to alcoholism. METHODS In our case control study we analyzed DNA samples from 799… CONTINUE READING

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