The association between circulating secreted protein acidic and rich in cysteine (SPARC) and glycosylated haemoglobin (HbA(1c)) during lifestyle-modified weight reduction intervention in obese male subjects.

@article{Kotani2011TheAB,
  title={The association between circulating secreted protein acidic and rich in cysteine (SPARC) and glycosylated haemoglobin (HbA(1c)) during lifestyle-modified weight reduction intervention in obese male subjects.},
  author={Kazuhiko Kotani and Tetsuo Yamada and Nobuyuki Taniguchi},
  journal={The Journal of international medical research},
  year={2011},
  volume={39 2},
  pages={528-32}
}
The physiological role and clinical relevance of circulating secreted protein acidic and rich in cysteine (SPARC, or osteonectin) is still poorly understood. This study investigated the correlation between circulating SPARC and metabolic variables, including glucose and glycosylated haemoglobin (HbA(1c)), during a diet and exercise modified weight reduction intervention programme. Changes in plasma SPARC levels and several metabolic variables were analysed in asymptomatically obese, nondiabetic… CONTINUE READING