The association between cholangiooaroinoma and hereditary nonpolyposis colorectal carcinoma

@article{Mecklin1992TheAB,
  title={The association between cholangiooaroinoma and hereditary nonpolyposis colorectal carcinoma},
  author={Jukka-Pekka Mecklin and Heikki J{\"a}rvinen and Martti Virolainen},
  journal={Cancer},
  year={1992},
  volume={69}
}
Eighteen patients with a biliopancreatic carcinoma in 15 different cancer family syndrome (CFS) families were studied. Only families with three or more first‐degree relatives with colorectal carcinoma were included, and other characteristics of CFS were required in at least two cases. In 14 patients, the histologic specimen was available for reevaluation. In 11 (79%), the tumor was confirmed as a carcinoma of the biliary tract or papilla of Vater. In three (21%), carcinoma of the pancreas was… 

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