The association between biological rhythms, depression, and functioning in bipolar disorder: a large multi-center study.

@article{Pinho2016TheAB,
  title={The association between biological rhythms, depression, and functioning in bipolar disorder: a large multi-center study.},
  author={Maria do Ros{\'a}rio de Pinho and Manpreet Sehmbi and Lauren E. Cudney and M{\'a}rcia Kauer-Sant'anna and Pedro Magalh{\~a}es and Mar{\'i}a Reinares and Caterina del Mar Bonn{\'i}n and Roberto Sassi and Fl{\'a}vio Pereira Kapczinski and Francesc Colom and Eduard Vieta and Benicio N. Frey and Annelise Ribeiro da Rosa},
  journal={Acta psychiatrica Scandinavica},
  year={2016},
  volume={133 2},
  pages={
          102-108
        }
}
OBJECTIVE We examined the relationship between biological rhythms and severity of depressive symptoms in subjects with bipolar disorder and the effects of biological rhythms alterations on functional impairment. METHOD Bipolar patients (n = 260) and healthy controls (n = 191) were recruited from mood disorders programs in three sites (Spain, Brazil, and Canada). Parameters of biological rhythms were measured using the Biological Rhythms Assessment in Neuropsychiatry (BRIAN), an interviewer… CONTINUE READING
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