The association between MLH1 -93 G>A polymorphism of DNA mismatch repair and cancer susceptibility: a meta-analysis.

@article{Pan2011TheAB,
  title={The association between MLH1 -93 G>A polymorphism of DNA mismatch repair and cancer susceptibility: a meta-analysis.},
  author={Xinmin Pan and Wen-Zhong Yang and G. Xu and P. Bai and Hao-jie Qin and Lu-shun Zhang and X. Zhai and M. Tang and W. Deng and L. Zhang and L. Gao},
  journal={Mutagenesis},
  year={2011},
  volume={26 5},
  pages={
          667-73
        }
}
  • Xinmin Pan, Wen-Zhong Yang, +8 authors L. Gao
  • Published 2011
  • Medicine
  • Mutagenesis
  • DNA mismatch repair, known as a fundamentally biological pathway, plays key roles in maintaining genomic stability, eliminating mismatch bases and preventing both mutagenesis in the short term and cancerogenesis in the long term. Polymorphisms of MLH1 in individuals may have an effect on the DNA repair capacity and therefore on cancer risk. Recently, emerging studies have been done to evaluate the association between MLH1 -93 G/A polymorphism and cancer risk in diverse populations. However, the… CONTINUE READING
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