The association between ATM D1853N polymorphism and breast cancer susceptibility: a meta-analysis

  title={The association between ATM D1853N polymorphism and breast cancer susceptibility: a meta-analysis},
  author={L. Gao and Xinmin Pan and H. Sun and X. Wang and L. Rao and Li-juan Li and Weibo Liang and Meili Lv and Wen-Zhong Yang and L. Zhang},
  journal={Journal of Experimental & Clinical Cancer Research : CR},
  pages={117 - 117}
  • L. Gao, Xinmin Pan, +7 authors L. Zhang
  • Published 2010
  • Biology, Medicine
  • Journal of Experimental & Clinical Cancer Research : CR
  • BackgroundEmerging evidence suggests that ataxia telangiectasia-mutated (ATM) is involved in numerous damage repair signaling pathways and cell-cycle checkpoints. Heterozygous carriers of ATM-mutations have an increased risk for the development of breast cancer. The purpose of this study is to evaluate the association between ATM exon39 5557G > A (D1853N, rs1801516) polymorphism and breast cancer susceptibility with the use of a meta-analysis.MethodsBy searching PubMed and Embase databases, a… CONTINUE READING
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