The association and linkage of the HLA-A2 class I allele with autism.

@article{Torres2006TheAA,
  title={The association and linkage of the HLA-A2 class I allele with autism.},
  author={Anthony R. Torres and Thayne L Sweeten and Adele Cutler and Brent J Bedke and Melanie Fillmore and E Gene Stubbs and Dennis Odell},
  journal={Human immunology},
  year={2006},
  volume={67 4-5},
  pages={346-51}
}
Previous research has revealed associations between autism and immune genes located in the human leukocyte antigen (HLA). To better understand which HLA genetic loci may be associated with autism, we compared the class I HLA-A and -B alleles in autistic probands with case control subjects from Caucasian families. The frequency of HLA-A2 alleles was significantly increased in autistic subjects compared with normal allelic frequencies from the National Marrow Donors Program (NMDP) (p = 0.0043… CONTINUE READING