The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells.

@article{CurtVaresano2016TheAP,
  title={The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells.},
  author={Aur{\'e}lie Curt-Varesano and Laurence Braun and Caroline Ranquet and Mohamed-Ali Hakimi and Alexandre Bougdour},
  journal={Cellular microbiology},
  year={2016},
  volume={18 2},
  pages={
          151-67
        }
}
Toxoplasma gondii and Plasmodium species are obligatory intracellular parasites that export proteins into the infected cells in order to interfere with host-signalling pathways, acquire nutrients or evade host defense mechanisms. With regard to export mechanism, a wealth of information in Plasmodium spp. is available, while the mechanisms operating in T. gondii remain uncertain. The recent discovery of exported proteins in T. gondii, mainly represented by dense granule resident proteins, might… CONTINUE READING
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