The aryl hydrocarbon receptor pathway and sexual differentiation of neuroendocrine functions.

@article{Petersen2006TheAH,
  title={The aryl hydrocarbon receptor pathway and sexual differentiation of neuroendocrine functions.},
  author={Sandra L. Petersen and Sudha Krishnan and Edward D Hudgens},
  journal={Endocrinology},
  year={2006},
  volume={147 6 Suppl},
  pages={S33-42}
}
Historically, much of the research on health effects of environmental pollutants focused on ascertaining whether compounds were carcinogenic. More recent findings show that environmental contaminants also exert insidious effects by disrupting hormone action. Of particular concern are findings that developmental exposure to dioxins, chemicals that act through the aryl hydrocarbon receptor pathway, permanently alters sexually differentiated neural functions in animal models. In this review, we… CONTINUE READING

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