The architecture of long-range haplotypes shared within and across populations.

  title={The architecture of long-range haplotypes shared within and across populations.},
  author={Alexander Gusev and Pier Francesco Palamara and Gregory W. Aponte and Zhong Zhuang and Ariel Darvasi and Peter A. Gregersen and Itsik Pe'er},
  journal={Molecular biology and evolution},
  volume={29 2},
Homologous long segments along the genomes of close or remote relatives that are identical by descent (IBD) from a common ancestor provide clues for recent events in human genetics. We set out to extensively map such IBD segments in large cohorts and investigate their distribution within and across different populations. We report analysis of several data sets, demonstrating that IBD is more common than expected by naïve models of population genetics. We show that the frequency of IBD pairs is… CONTINUE READING

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