The architecture of gene expression: integrating dispersed cis-regulatory modules into coherent regulatory domains.


Specificity and precision of expression are essential for the genes that regulate developmental processes. The specialized cis-acting modules, such as enhancers, that define gene expression patterns can be distributed across large regions, raising questions about the nature of the mechanisms that underline their action. Recent data has exposed the… (More)
DOI: 10.1016/j.gde.2014.03.014


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