The architect who never sleeps: Tumor-induced plasticity

@inproceedings{Varga2014TheAW,
  title={The architect who never sleeps: Tumor-induced plasticity},
  author={Julia Varga and Tiago De Oliveira and Florian R Greten},
  booktitle={FEBS letters},
  year={2014}
}
Tumor cell plasticity is an event that has been observed in several malignancies. In fact, most of the solid tumors are characterized by cellular heterogeneity and undergo constant changes as the tumor develops. The increased plasticity displayed by these cells allows them to acquire additional properties, enabling epithelial-mesenchymal transitions, dedifferentiation and the acquisition of stem cell-like properties. Here we discuss the particular importance of an inflammatory microenvironment… CONTINUE READING
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