The arachidonic acid cascade is involved in the masculinizing action of testosterone on embryonic external genitalia in mice.

@article{Gupta1986TheAA,
  title={The arachidonic acid cascade is involved in the masculinizing action of testosterone on embryonic external genitalia in mice.},
  author={C. Gupta and A. Goldman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1986},
  volume={83 12},
  pages={
          4346-9
        }
}
  • C. Gupta, A. Goldman
  • Published 1986
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
We have evaluated whether the arachidonic acid cascade may be involved in the folding and fusion of the penis and scrotum in masculine differentiation, a possibility raised by recent observations of the involvement of the arachidonic acid cascade in the analogous embryonic processes of elevation and fusion of the palatal shelves and of folding and fusion of the neural tube. To test this hypothesis, during embryonic masculine differentiation in mice of the B10.A strain, we administered certain… Expand
Activation of Phospholipases during Masculine Differentiation of Embryonic Genitalia
  • C. Gupta
  • Biology, Medicine
  • Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
  • 1988
Prostaglandins masculinize the mouse genital tract.
  • C. Gupta
  • Biology, Medicine
  • Endocrinology
  • 1989
Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.
Synergistic Disruption of External Male Sex Organ Development by a Mixture of Four Antiandrogens
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