The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey.

@article{Ioannidis2007TheAO,
  title={The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey.},
  author={John P. A. Ioannidis and Thomas A. Trikalinos},
  journal={CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne},
  year={2007},
  volume={176 8},
  pages={1091-6}
}
BACKGROUND Statistical tests for funnel-plot asymmetry are common in meta-analyses. Inappropriate application can generate misleading inferences about publication bias. We aimed to measure, in a survey of meta-analyses, how frequently the application of these tests would be not meaningful or inappropriate. METHODS We evaluated all meta-analyses of binary outcomes with é 3 studies in the Cochrane Database of Systematic Reviews (2003, issue 2). A separate, restricted analysis was confined to… CONTINUE READING
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