The application of randomly amplified DNA analysis in the molecular epidemiology of microorganisms.


The polymerase chain reaction (PCR) has essentially been designed to amplify specific regions within DNA molecules. This requires knowledge of the local nucleic acid sequence to design primer oligonucleotides. However, to generate DNA fingerprints, the PCR can be modified in a way that facilitates the random amplification of elements for which the precise… (More)
DOI: 10.1007/978-1-60327-999-4_4