The application of biofilm science to the study and control of chronic bacterial infections.

@article{Costerton2003TheAO,
  title={The application of biofilm science to the study and control of chronic bacterial infections.},
  author={William J. Costerton and Richard H Veeh and Mark E. Shirtliff and Mark E Pasmore and Christopher Post and G. Ehrlich},
  journal={The Journal of clinical investigation},
  year={2003},
  volume={112 10},
  pages={1466-77}
}
Unequivocal direct observations have established that the bacteria that cause device-related and other chronic infections grow in matrix-enclosed biofilms. The diagnostic and therapeutic strategies that have served us so well in the partial eradication of acute epidemic bacterial diseases have not yielded accurate data or favorable outcomes when applied to these biofilm diseases. We discuss the potential benefits of the application of the new methods and concepts developed by biofilm science… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 58 references

Biofilms as complex differentiated communities.

Annual review of microbiology • 2002
View 5 Excerpts
Highly Influenced

Basic science in musculoskeletal infections

M. E. Shirtliff, J. G. Leid, J. W. Costerton
In Musculoskeletal Infections • 2003

LuxS quorum sensing: more than just a numbers game.

Current opinion in microbiology • 2003
View 1 Excerpt

Molecular and translational research approaches for the study of bacterial pathogenesis in otitis media

K. Shen, X. Wang, J. C. Post, G. D. Ehrlich
2003
View 1 Excerpt

Use of the quorum-sensing inhibitor RNAIIIinhibiting peptide to prevent biofilm formation in vivo by drug-resistant Staphylococcus epidermidis

N Balaban
J. Infect • 2003
View 2 Excerpts

A proteomic study of Escherichia coli O 157 : H 7 NCTC 12900 cultivated in biofilm or in planktonic growth mode

B. S. Miller, M. R. Diaz-Torres
FEMS Microbiol . Lett . • 2002

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