The application of a crosslinked pectin-based wafer matrix for gradual buccal drug delivery.

Abstract

The purpose of this study was to develop crosslinked wafer matrices and establish the influence of the crosslinker type and processing sequence on achieving gradual buccal drug delivery. Three sets of drug-loaded crosslinked pectin wafers were produced employing the model water-soluble antihistamine, diphenhydramine and were compared with noncrosslinked… (More)
DOI: 10.1002/jbm.b.32668

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