The application of Markov chain Monte Carlo methods to radiation hybrid mapping


The ordering of genetic loci is central to genetic mapping at all levels. Markov chain Monte Carlo (MCMC) techniques can provide estimates of the posterior density of orders while accounting naturally for missing data, data errors and unknown parameters. Such techniques have been proposed for mapping problems such as linkage mapping and radiation hybrid… (More)
DOI: 10.1145/267521.267541


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