The application of HSP70 as a target for gene therapy.

  title={The application of HSP70 as a target for gene therapy.},
  author={Zhen Zheng and Midori A Yenari},
  journal={Frontiers in bioscience : a journal and virtual library},
The 70-kDa heat shock proteins (HSP70s) are well-studied and characterized heat shock proteins (HSPs). They constitute essential components of a quality control system of protein synthesis, and function as molecular chaperones to prevent proteins from misfolding and aggregating during both de novo synthesis and under conditions of stress. Moreover, it is now well established that HSP70s play important cytoprotective roles in various pathological settings. Recognition of molecular chaperone and… CONTINUE READING

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