The apparent diffusion coefficient is strongly correlated with extracellular volume, a measure of myocardial fibrosis, and subclinical cardiomyopathy in patients with systemic lupus erythematosus.

Background Extracellular volume (ECV) has been histologically validated as a non-invasive quantitative index of myocardial fibrosis that does not require the use of contrast, which is contraindicated in patients with renal insufficiency. Purpose To evaluate the correlation between the contrast-free apparent diffusion coefficient (ADC) and ECV, an index of… CONTINUE READING