The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans.

@article{Freedman2010TheAL,
  title={The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans.},
  author={Barry I. Freedman and Jeffrey B. Kopp and Carl D. Langefeld and Giulio Genovese and David J. Friedman and George W. Nelson and Cheryl A. Winkler and Donald W. Bowden and Martin R. Pollak},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2010},
  volume={21 9},
  pages={1422-6}
}
Mapping by admixture linkage disequilibrium (LD) detected strong association between nonmuscle myosin heavy chain 9 gene (MYH9) variants on chromosome 22 and nondiabetic nephropathy in African Americans. MYH9-related variants were posited to be the probable, but not necessarily the definitive, causal variants as a result of impressive statistical evidence of association, renal expression, and a role in autosomal dominant MYH9 disorders characterized by progressive glomerulosclerosis (Epstein… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 102 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 22 references

Apolipoprotein L1, a novel Bcl-2 CLINICAL COMMENTARY www.jasn.org

  • G Wan, S Zhaorigetu, Z Liu, R Kaini, Z Jiang, CA Hu
  • J Am Soc Nephrol
  • 2010

AASK Investigators: Association analysis of the non-muscle myosin heavy chain 9 gene (MYH9) in hypertensive nephropathy: African American Study of Kidney Disease and Hypertension (AASK)

  • MS Lipkowitz, S Iyengar, +15 authors EP Bottinger
  • J Am Soc Nephrol 20: 56A,
  • 2009

Association analysis of the nonmuscle myosin heavy chain 9 gene ( MYH 9 ) in hypertensive nephropathy : African American Study of Kidney Disease and Hypertension ( AASK )

  • MS Lipkowitz, S Iyengar, +13 authors EP Bottinger
  • J Am Soc Neph
  • 2009

Similar Papers

Loading similar papers…