The anxiolytic-like effect of an essential oil derived from Spiranthera odoratissima A. St. Hil. leaves and its major component, β-caryophyllene, in male mice

@article{Galdino2012TheAE,
  title={The anxiolytic-like effect of an essential oil derived from Spiranthera odoratissima A. St. Hil. leaves and its major component, β-caryophyllene, in male mice},
  author={Pablinny Moreira Galdino and Marcus Vin{\'i}cius Mariano Nascimento and Iziara Ferreira Florentino and Roberta Campos Lino and James Oluwagbamigbe Fajemiroye and Beatriz Abdallah Chaibub and Jos{\'e} Realino de Paula and Thereza Christina Monteiro de Lima and Elson A Costa},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2012},
  volume={38},
  pages={276-284}
}
Spiranthera odoratissima A. St. Hil. (manacá) is used in folk medicine to treat renal and hepatic diseases, stomachache, headaches and rheumatism. A central nervous system (CNS) depressant effect of the hexane fraction from the ethanolic extract of this plant has been described. β-caryophyllene, the main component of this essential oil, is a sesquiterpene compound with anti-inflammatory properties that has been found in essential oils derived from several medicinal plants. This work is aimed to… CONTINUE READING
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