The anxiogenic action of Ro 5-4864 is reversed by phenytoin.

@article{File1983TheAA,
  title={The anxiogenic action of Ro 5-4864 is reversed by phenytoin.},
  author={S. E. File and Richard G. Lister},
  journal={Neuroscience letters},
  year={1983},
  volume={35 1},
  pages={93-6}
}
Ro 5-4864, a selective ligand for the benzodiazepine micromolar and peripheral receptors, had a significant dose-related (5-20 mg/kg) anxiogenic action in the social interaction test of anxiety. This anxiogenic effect was reversed by phenytoin (10 mg/kg), a ligand for the micromolar receptors, but unaffected by the isoquinoline PK 11195 (10 mg/kg), a ligand for the peripheral receptors. 

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