The antithrombogenic potential of a polyhedral oligomeric silsesquioxane (POSS) nanocomposite.

@article{Kannan2006TheAP,
  title={The antithrombogenic potential of a polyhedral oligomeric silsesquioxane (POSS) nanocomposite.},
  author={Ruben Yap Kannan and Henryk J. Salacinski and Jaco de Groot and Ian Clatworthy and Laurent Bozec and Mike C Horton and Peter Edward Butler and Alexander M. Seifalian},
  journal={Biomacromolecules},
  year={2006},
  volume={7 1},
  pages={215-23}
}
We have developed a nanocomposite using a silica nanocomposite polyhedral oligomeric silsesquioxane (POSS) and poly(carbonate-urea)urethane (PCU) for potential use in cardiovascular bypass grafts and the microvascular component of artificial capillary beds. In this study, we sought to compare its antithrombogenicity to that of conventional polymers used in vascular bypass grafts so as to improve upon current patency rates, particularly in the microvascular setting. Using atomic force microscopy… CONTINUE READING

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