The antispasmogenic action on guinea-pig ileum of a fraction obtained from the toxic skin secretion of the stonefish, Synanceia trachynis.

@article{Cameron1982TheAA,
  title={The antispasmogenic action on guinea-pig ileum of a fraction obtained from the toxic skin secretion of the stonefish, Synanceia trachynis.},
  author={A. Cameron and R. Lewis},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={1982},
  volume={20 6},
  pages={
          991-1000
        }
}
  • A. Cameron, R. Lewis
  • Published 1982
  • Biology, Medicine
  • Toxicon : official journal of the International Society on Toxinology
  • The toxic skin tubercle gland secretion of the stonefish, Synanceia trachynis, contains a smooth muscle antispasmogen that is readily distinguished from papaverine, verapamil and both alpha and beta adrenoreceptor agonists. At 15 micrograms/ml, the toxin containing fraction markedly inhibited the phasic response and had a lesser inhibitory effect on the tonic response of acetylcholine-and KCl-induced contractures of guinea-pig ileum, while at 50 micrograms/ml, the toxin markedly inhibited both… CONTINUE READING
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