The antipsychotic amisulpride: ultrastructural evidence of its secretory activity in salivary glands.


OBJECTIVE Amisulpride is reported to inhibit clozapine-induced sialorrhea. Preclinically, clozapine evokes muscarinic-M1-type-mediated secretion that, however, amisulpride does not reduce. Instead, amisulpride, without causing any overt secretion per se, enhances both nerve- and autonomimetic-evoked salivation by unknown mechanism(s). Hypothesizing that… (More)
DOI: 10.1111/odi.12209


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