The antioxidative and antilipidemic effects of different molecular weight chitosans in metabolic syndrome model rats.

@article{Anraku2010TheAA,
  title={The antioxidative and antilipidemic effects of different molecular weight chitosans in metabolic syndrome model rats.},
  author={Makoto Anraku and Akihiro Michihara and Taira Yasufuku and Kenji Akasaki and Daiju Tsuchiya and Hiroaki Nishio and Toru Maruyama and Masaki Otagiri and Yuji Maezaki and Yuko Kondo and Hisao Tomida},
  journal={Biological & pharmaceutical bulletin},
  year={2010},
  volume={33 12},
  pages={1994-8}
}
The effect of high and low molecular weight chitosans (HMC; 1000 kDa, LMC; 30 kDa) on oxidative stress and hypercholesterolemia was investigated using male 6-week-old Wistar Kyoto rats as a normal model (Normal-rats) and spontaneously hypertensive rat/ND mcr-cp (SHP/ND) as a metabolic syndrome model (MS-rats), respectively. In Normal-rats, the ingestion of both chitosans over a 4 week period resulted in a significant decrease in total body weight (BW), glucose (Gl), triglyceride (TG), low… CONTINUE READING
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