The antioxidant glutathione in the fish cell lines EPC and BCF-2: response to model pro-oxidants as measured by three different fluorescent dyes.

@article{Jos2009TheAG,
  title={The antioxidant glutathione in the fish cell lines EPC and BCF-2: response to model pro-oxidants as measured by three different fluorescent dyes.},
  author={{\'A}ngeles Jos and Ana M Came{\'a}n and Stephan Pflugmacher and Helmut Segner},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2009},
  volume={23 3},
  pages={546-53}
}
Reduced glutathione (GSH) protects cells against injury by oxidative stress and maintains a range of vital functions. In vitro cell cultures have been used as experimental models to study the role of GSH in chemical toxicity in mammals; however, this approach has been rarely used with fish cells to date. The present study aimed to evaluate sensitivity and specificity of three fluorescent dyes for measuring pro-oxidant-induced changes of GSH contents in fish cell lines: monochlorobimane (mBCl… CONTINUE READING
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