The antioxidant action of tamoxifen and its metabolites Inhibition of lipid peroxidation

@article{Wiseman1990TheAA,
  title={The antioxidant action of tamoxifen and its metabolites Inhibition of lipid peroxidation},
  author={H. Wiseman and M. J. Laughton and H. Arnstein and M. Cannon and B. Halliwell},
  journal={FEBS Letters},
  year={1990},
  volume={263}
}
The anti‐oestrogen drug tamoxifen is an inhibitor of lipid peroxidation in rat liver microsomes and in phospholipid liposomes. Its cis isomer and N‐desmethyl form are weaker inhibitors, but 4‐hydroxytamoxifen is much more powerful. It is possible that the antioxidant property of tamoxifen might contribute to its biological actions. 
Curcuminoids as Potent Inhibitors of Lipid Peroxidation
  • Sreejayan, M. Rao
  • Chemistry, Medicine
  • The Journal of pharmacy and pharmacology
  • 1994
Melatonin Enhances Tamoxifen's Ability to Prevent the Reduction in Microsomal Membrane Fluidity Induced by Lipid Peroxidation
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