The antigenic switching network of Plasmodium falciparum and its implications for the immuno-epidemiology of malaria

Abstract

Antigenic variation in the human malaria parasite Plasmodium falciparum involves sequential and mutually exclusive expression of members of the var multi-gene family and appears to follow a non-random pattern. In this study, using a detailed in vitro gene transcription analysis of the culture-adapted HB3 strain of P. falciparum, we show that antigenic… (More)
DOI: 10.7554/eLife.01074

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