The antigenic characteristics and the significance of the adenine nucleotide translocator as a major autoantigen to antimitochondrial antibodies in dilated cardiomyopathy.

@article{Schultheiss1985TheAC,
  title={The antigenic characteristics and the significance of the adenine nucleotide translocator as a major autoantigen to antimitochondrial antibodies in dilated cardiomyopathy.},
  author={Heinz Peter Schultheiss and P W Schwimmbeck and Heinz D. Bolte and Martin Klingenberg},
  journal={Advances in myocardiology},
  year={1985},
  volume={6},
  pages={
          311-27
        }
}
To obtain further knowledge of the antigen-antibody system, immunochemical characterization of the adenine nucleotide translocator was achieved by crossed immunoelectrophoresis, immunoreplica technique, radioimmunoassay, immunoabsorption studies, and nucleotide-transport measurements. Sera of 18 patients with proven congestive cardiomyopathy (CCM) were tested. On the adenine nucleotide translocator (ANT) from heart, kidney, and liver, organ-specific antigenic determinants were demonstrable… CONTINUE READING

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