The antidiabetic effect of ginsenoside Rb2 via activation of AMPK.

@article{Lee2011TheAE,
  title={The antidiabetic effect of ginsenoside Rb2 via activation of AMPK.},
  author={Kyoung-Tae Lee and Tae Woo Jung and Hak-ju Lee and Seul-Gi Kim and Yu-Su Shin and Wan-Kyunn Whang},
  journal={Archives of pharmacal research},
  year={2011},
  volume={34 7},
  pages={1201-8}
}
Ginsenosides, which are active compounds found in ginseng (Panax ginseng), are used as antidiabetic treatments. The aim of this study was to determine whether Rb2, a type of ginsenoside, regulates hepatic gluconeogenesis through AMP-activated protein kinase (AMPK) and the orphan nuclear receptor small heterodimer partner (SHP) in hyperlipidemic conditions used as an in vitro model of type 2 diabetes. Considering these results, we concluded that Rb2 may inhibit palmitate-induced gluconeogenesis… CONTINUE READING

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References

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Showing 1-10 of 41 references

Beneficial effects of IH901 on glucose and lipid metabolisms via activating adenosine monophosphateactivated protein kinase and phosphatidylinositol3 kinase pathways

  • B. B. Zhang, G. Zhou, C. Li
  • Metabolism
  • 2011

, an active component of Panax ginseng , stimulates glucose uptake in C 2 C 12 myotubes through an AMPKdependent mechanism

  • M. Lee, J. Hwang, +5 authors Ginsenoside Rc
  • J . Ethnopharmacol .
  • 2010
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