The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors.

@article{Wang2008TheAE,
  title={The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors.},
  author={Rui Wang and Ying Xu and H Wu and Ying-bo Li and Yuhua Li and J Guo and Xue-Jun Li},
  journal={European journal of pharmacology},
  year={2008},
  volume={578 1},
  pages={43-50}
}
Curcuma longa is a main constituent of many traditional Chinese medicines, such as Xiaoyao-san, used to manage mental disorders effectively. Curcumin is a major active component of C. longa and its antidepressant-like effect has been previously demonstrated in the forced swimming test. The purpose of this study was to explore the possible contribution of serotonin (5-HT) receptors in the behavioral effects induced by curcumin in this animal model of depression. 5-HT was depleted by the… CONTINUE READING
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