The anticonvulsant levetiracetam potentiates alcohol consumption in non-treatment seeking alcohol abusers.

@article{Mitchell2012TheAL,
  title={The anticonvulsant levetiracetam potentiates alcohol consumption in non-treatment seeking alcohol abusers.},
  author={Jennifer M Mitchell and Leah E Grossman and Allison R. Coker and Robert O Messing},
  journal={Journal of clinical psychopharmacology},
  year={2012},
  volume={32 2},
  pages={269-72}
}
BACKGROUND Levetiracetam (Keppra) is a commonly prescribed anticonvulsant that has been shown to attenuate alcohol consumption in an open-label study of treatment-seeking, alcohol-dependent subjects. METHODS Here we performed a 42-day placebo-controlled, double-blind, randomized crossover trial to evaluate the effects of levetiracetam on moderate to heavy drinkers receiving either a low (500-1000 g/d) or a moderate (1000-2000 g/d) dose. Electronic diaries were used to monitor daily ethanol… CONTINUE READING