The anticoagulant mechanism of action of heparin in contact-activated plasma: inhibition of factor X activation.


The effects of heparin on the activation of blood coagulation factors IX and X in contact-activated plasma were determined in the present study. In the presence and absence of 0.5 U/mL heparin, the amounts of factor IX that were cleaved 30 minutes after the addition of calcium and phospholipid to plasma exposed to glass (ie, contact activated) were… (More)

4 Figures and Tables


  • Presentations referencing similar topics