The antibody combining site: retrospect and prospect.

Abstract

The evolution of our current understanding of how antibodies exert their biological functions has consisted of periods of intense activity punctuated by periods of rather slow progress. Further development of Ehrlich's conceptual advances (which had laid the foundations of molecular immunology) was frustrated by the limitations of the prevailing theoretical… (More)
DOI: 10.1016/0167-5699(87)90237-4

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