The antiallergic drug oxatomide promotes human eosinophil apoptosis and suppresses IL-5-induced eosinophil survival.

@article{Domae2003TheAD,
  title={The antiallergic drug oxatomide promotes human eosinophil apoptosis and suppresses IL-5-induced eosinophil survival.},
  author={Mariko Domae and Hironori Sagara and Morito Sakaue and Takeshi Fukuda and Yuichiro Kamikawa},
  journal={The Journal of allergy and clinical immunology},
  year={2003},
  volume={111 3},
  pages={567-72}
}
BACKGROUND Eosinophils accumulated in sites of allergic inflammation are thought to play a crucial role in the pathogenesis of allergic disorders including asthma, allergic rhinitis, and atopic dermatitis, and tissue eosinophilia is attributable to increased eosinophil survival or decreased eosinophil apoptosis. OBJECTIVE Effects of the antiallergic… CONTINUE READING