The antiadrenolytic action of ergotamine.

@article{King1949TheAA,
  title={The antiadrenolytic action of ergotamine.},
  author={T. King and T. Kopp{\'a}nyi},
  journal={Journal of the American Pharmaceutical Association. American Pharmaceutical Association},
  year={1949},
  volume={38 6},
  pages={
          346-8
        }
}
  • T. King, T. Koppányi
  • Published 1949
  • Medicine
  • Journal of the American Pharmaceutical Association. American Pharmaceutical Association
  • The vasomotor reversal of Dale is generally considered to be due to depression of the vasoconstrictor, but not of the vasodilator sympathetic neuro-effectors, leaving epinephrine free to stimulate the vasodilator, but not the vasoconstrictor sympathetc terminations. This phenomenon, called adrenolysis, may be caused by ergotamine, dibenamine, and other drugs. In dogs under nembutal anesthesia it was shown that ergotamine at certain dose levels not only does not reverse, but actually potentiates… CONTINUE READING

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