The anti-tumour activity of ifosfamide on heterotransplanted testicular cancer cell lines remains unaltered by the uroprotector mesna.

Abstract

Ifosfamide is clinically used in combination chemotherapy regimens for the treatment of patients with high-grade lymphomas, sarcomas and metastatic germ cell tumours. In order to reduce the oxazophosphorine-related urothelial toxicity, sodium mercaptoethane sulphonate (mesna) is used in different schedules following the administration of ifosfamide. The… (More)
DOI: 10.1038/bjc.1994.167

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@article{Bokemeyer1994TheAA, title={The anti-tumour activity of ifosfamide on heterotransplanted testicular cancer cell lines remains unaltered by the uroprotector mesna.}, author={C Carsten Bokemeyer and H. - J. Schmoll and Elizabeth A. Ludwig and Andreas Harstrick and T. Dunn and Jonathan Casper}, journal={British Journal of Cancer}, year={1994}, volume={69}, pages={863 - 867} }