The anti-thrombotic activity of surfactins.

@article{Lim2005TheAA,
  title={The anti-thrombotic activity of surfactins.},
  author={Jong-Hwan Lim and B. Park and M. Kim and Mi-Hyun Hwang and M. Rhee and S. Park and H. Yun},
  journal={Journal of veterinary science},
  year={2005},
  volume={6 4},
  pages={
          353-5
        }
}
  • Jong-Hwan Lim, B. Park, +4 authors H. Yun
  • Published 2005
  • Chemistry, Medicine
  • Journal of veterinary science
  • Platelet aggregation was inhibited and the density of platelet-rich plasma (PRP) clots was decreased by the preincubation of PRP with surfactins, an acidic lipopeptide of Bacillus subtilis complex BC1212 isolated from soybean paste, in dose-dependent manner. Our findings suggest that surfactins are able to prevent a platelet aggregation leading to an inhibition of additional fibrin clot formation, and to enhance fibrinolysis with facilitated diffusion of fibrinolytic agents. 
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    References

    SHOWING 1-10 OF 12 REFERENCES
    Enhancement of plasminogen activation by surfactin C: augmentation of fibrinolysis in vitro and in vivo.
    • 60
    Interactions of bioactive lipopeptides, iturin A and surfactin from Bacillus subtilis
    • 65
    Dynamics of thrombus formation.
    • 14
    Separation and Characterization of Surfactin Isoforms Produced by Bacillus subtilis OKB 105
    • 106
    [Study on surfactin, a cyclic depsipeptide. I. Isolation and structure of eight surfuctin analogs produced by Bacillus natto KMD 2311].
    • 14
    Structural and conformational studies of [Ile7] and [Leu7]surfactins from Bacillus subtilis natto.
    • 84
    Identification of amino acid substitutions in the lipopeptide surfactin using 2D NMR spectroscopy.
    • 72
    Satisfactory separation and MS-MS spectrometry of six surfactins isolated from Bacillus subtilis natto.
    • 42
    Microbial production of surfactants and their commercial potential.
    • 1,398
    • PDF
    Molecular genetics of biosurfactnats production
    • Curr Opin Microbiol 1985,
    • 1985