The anti-parasitic effects of nitric oxide.

  title={The anti-parasitic effects of nitric oxide.},
  author={Paolo Ascenzi and A Alessio Bocedi and Luigi Gradoni},
  journal={IUBMB life},
  volume={55 10-11},
Endogenous and exogenous nitric oxide (NO) possesses antiparasitic effects on both Protozoa and Metazoa. However, NO production requires a tight control to limit cytotoxic damage to the host's own cells. The best known parasitic macromolecular targets for NO(-donors) are cysteine proteases, which are relevant in several aspects of the parasite life cycle… CONTINUE READING