The anti-inflammatory effect of exercise.

@article{Petersen2005TheAE,
  title={The anti-inflammatory effect of exercise.},
  author={Anne Marie Winther Petersen and Bente Klarlund Pedersen},
  journal={Journal of applied physiology},
  year={2005},
  volume={98 4},
  pages={
          1154-62
        }
}
Regular exercise offers protection against all-cause mortality, primarily by protection against cardiovascular disease and Type 2 diabetes mellitus. The latter disorders have been associated with chronic low-grade systemic inflammation reflected by a two- to threefold elevated level of several cytokines. Adipose tissue contributes to the production of TNF-alpha, which is reflected by elevated levels of soluble TNF-alpha receptors, IL-6, IL-1 receptor antagonist, and C-reactive protein. We… Expand
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The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control.
TLDR
IL-6 was introduced as the first myokine, defined as a cytokine, that is produced and released by contracting skeletal muscle fibres, exerting its effects in other organs of the body, which may be involved in mediating the beneficial health effects against chronic diseases associated with low-grade inflammation such as diabetes and cardiovascular diseases. Expand
The role of IL-6 in mediating the anti-inflammatory effects of exercise.
  • A. M. Petersen, B. Pedersen
  • Medicine
  • Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
  • 2006
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This review focuses on the anti-inflammatory effects of Exercise and how this may contribute to mediate the beneficial health effects of exercise training in patients with chronic diseases associated with chronic low-grade inflammation. Expand
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While waiting for the outcome of long-term clinical pharmacological trials, it should be emphasized that physical activity represents a natural strong anti-inflammatory intervention with little or no side effects. Expand
The effects of chronic exercise on the inflammatory cytokines interleukin-6 and tumor necrosis factor-α are different with age.
  • M. Moon, Bongjun Cho, +5 authors H. Jang
  • Biology, Medicine
  • Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
  • 2012
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It is suggested that chronic endurance exercise could influence the inflammatory response of hepatic tissues, as well as muscle, and that the effects of chronic endurance Exercise on inflammatory cytokine levels are different between old and young rats and an exercise program tailored for old subjects will be needed to obtain beneficial anti-inflammatory effects from exercise. Expand
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This paper reviews the studies describing elevatedIL-6 levels in obese patients and the role of adipocytes and adipose-tissue macrophages in the production of IL-6 and the effect on metabolism through several mechanisms, including adipose tissue-specific gene expression, triglyceride release, lipoprotein lipase downregulation, insulin sensitivity, and so on. Expand
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An overview of the impact of different modes and intensities of physical activity on vascular inflammation and thrombogenesis is provided. Expand
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The aim of the present study is to review the current evidence about the anti-inflammatory effects of exercise and toll-like receptors regulation on immune cells in humans to contribute to the protective effect of exercise against insulin resistance and the prevention of the development of metabolic diseases. Expand
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Analysis of available researches seem to confirm the efficacy of regular physical training as a nonpharmacological therapy having target chronic low-grade inflammation. Expand
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The anti-inflammatory effects of regular exercise may be mediated via a reduction in visceral fat mass (with a subsequent decreased release of adipokines) and the induction of an anti- inflammatory environment with each bout of exercise. Expand
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